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Dynamic Regulation of the Mitochondrial Proton Gradient during Cytosolic Calcium Elevations

Mitochondria extrude protons across their inner membrane to generate the mitochondrial membrane potential (ΔΨ(m)) and pH gradient (ΔpH(m)) that both power ATP synthesis. Mitochondrial uptake and efflux of many ions and metabolites are driven exclusively by ΔpH(m), whose in situ regulation is poorly...

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Detalhes bibliográficos
Main Authors: Poburko, Damon, Santo-Domingo, Jaime, Demaurex, Nicolas
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064219/
https://ncbi.nlm.nih.gov/pubmed/21224385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.159962
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