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Dynamic Regulation of the Mitochondrial Proton Gradient during Cytosolic Calcium Elevations

Mitochondria extrude protons across their inner membrane to generate the mitochondrial membrane potential (ΔΨ(m)) and pH gradient (ΔpH(m)) that both power ATP synthesis. Mitochondrial uptake and efflux of many ions and metabolites are driven exclusively by ΔpH(m), whose in situ regulation is poorly...

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Bibliografiske detaljer
Main Authors: Poburko, Damon, Santo-Domingo, Jaime, Demaurex, Nicolas
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Biochemistry and Molecular Biology 2011
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3064219/
https://ncbi.nlm.nih.gov/pubmed/21224385
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.159962
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