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Neuronal Activity and Glutamate Uptake Decrease Mitochondrial Mobility in Astrocytes and Position Mitochondria Near Glutamate Transporters

Within neurons, mitochondria are nonuniformly distributed and are retained at sites of high activity and metabolic demand. Glutamate transport and the concomitant activation of the Na(+)/K(+)-ATPase represent a substantial energetic demand on astrocytes. We hypothesized that mitochondrial mobility w...

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Bibliografiska uppgifter
Huvudupphovsmän: Jackson, Joshua G., O'Donnell, John C., Takano, Hajime, Coulter, Douglas A., Robinson, Michael B.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Society for Neuroscience 2014
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC3905137/
https://ncbi.nlm.nih.gov/pubmed/24478345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3510-13.2014
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