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Neuronal Activity and Glutamate Uptake Decrease Mitochondrial Mobility in Astrocytes and Position Mitochondria Near Glutamate Transporters

Within neurons, mitochondria are nonuniformly distributed and are retained at sites of high activity and metabolic demand. Glutamate transport and the concomitant activation of the Na(+)/K(+)-ATPase represent a substantial energetic demand on astrocytes. We hypothesized that mitochondrial mobility w...

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Autors principals: Jackson, Joshua G., O'Donnell, John C., Takano, Hajime, Coulter, Douglas A., Robinson, Michael B.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2014
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3905137/
https://ncbi.nlm.nih.gov/pubmed/24478345
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3510-13.2014
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