Influence of lever structure on myosin 5a walking

Using electron microscopy and image processing, we have observed myosin 5a modified with lever arms of different lengths (four, six, and eight calmodulin-binding IQ domains) and orientations walking along actin filaments. Step lengths were dependent on lever length: 8IQ > 6IQ > 4IQ, which is c...

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Autores principales: Oke, Olusola A., Burgess, Stan A., Forgacs, Eva, Knight, Peter J., Sakamoto, Takeshi, Sellers, James R., White, Howard, Trinick, John
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2010
Materias:
Biological Sciences
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823865/
https://ncbi.nlm.nih.gov/pubmed/20133809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0906907107
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