The SAH domain extends the functional length of the myosin lever

Stable, single alpha-helix (SAH) domains are widely distributed in the proteome, including in myosins, but their functions are unknown. To test whether SAH domains can act as levers, we replaced four of the six calmodulin-binding IQ motifs in the levers of mouse myosin 5a (Myo5) with the putative SA...

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Bibliografiska uppgifter
Huvudupphovsmän: Baboolal, Thomas G., Sakamoto, Takeshi, Forgacs, Eva, White, Howard D., Jackson, Scott M., Takagi, Yasuharu, Farrow, Rachel E., Molloy, Justin E., Knight, Peter J., Sellers, James R., Peckham, Michelle
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2009
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2794034/
https://ncbi.nlm.nih.gov/pubmed/20018767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0909851106
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