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Influence of lever structure on myosin 5a walking

Using electron microscopy and image processing, we have observed myosin 5a modified with lever arms of different lengths (four, six, and eight calmodulin-binding IQ domains) and orientations walking along actin filaments. Step lengths were dependent on lever length: 8IQ > 6IQ > 4IQ, which is c...

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Detalles Bibliográficos
Main Authors: Oke, Olusola A., Burgess, Stan A., Forgacs, Eva, Knight, Peter J., Sakamoto, Takeshi, Sellers, James R., White, Howard, Trinick, John
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2010
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823865/
https://ncbi.nlm.nih.gov/pubmed/20133809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0906907107
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