Influence of lever structure on myosin 5a walking

Using electron microscopy and image processing, we have observed myosin 5a modified with lever arms of different lengths (four, six, and eight calmodulin-binding IQ domains) and orientations walking along actin filaments. Step lengths were dependent on lever length: 8IQ > 6IQ > 4IQ, which is c...

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Bibliographic Details
Main Authors: Oke, Olusola A., Burgess, Stan A., Forgacs, Eva, Knight, Peter J., Sakamoto, Takeshi, Sellers, James R., White, Howard, Trinick, John
Format: Artigo
Language:Inglês
Published: National Academy of Sciences 2010
Subjects:
Biological Sciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823865/
https://ncbi.nlm.nih.gov/pubmed/20133809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0906907107
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