Influence of lever structure on myosin 5a walking

Using electron microscopy and image processing, we have observed myosin 5a modified with lever arms of different lengths (four, six, and eight calmodulin-binding IQ domains) and orientations walking along actin filaments. Step lengths were dependent on lever length: 8IQ > 6IQ > 4IQ, which is c...

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Bibliografiska uppgifter
Huvudupphovsmän: Oke, Olusola A., Burgess, Stan A., Forgacs, Eva, Knight, Peter J., Sakamoto, Takeshi, Sellers, James R., White, Howard, Trinick, John
Materialtyp: Artigo
Språk:Inglês
Publicerad: National Academy of Sciences 2010
Ämnen:
Biological Sciences
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823865/
https://ncbi.nlm.nih.gov/pubmed/20133809
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0906907107
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