Llwytho...

Leveraging APOBEC3 proteins to alter the HIV mutation rate and combat AIDS

At least two human APOBEC3 proteins – APOBEC3F and APOBEC3G – are capable of inhibiting HIV-1 replication by mutation of the viral cDNA. HIV-1 averts lethal restriction through its accessory protein Vif, which targets these APOBEC3 proteins for proteasomal degradation. The life-or-death interaction...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Hultquist, Judd F, Harris, Reuben S
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2822356/
https://ncbi.nlm.nih.gov/pubmed/20174454
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fvl.09.59
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