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D316 is critical for the enzymatic activity and HIV-1 restriction potential of human and rhesus APOBEC3B
APOBEC3B is one of seven human APOBEC3 DNA cytosine deaminases that function to inhibit the replication and persistence of retroelements and retroviruses. Human APOBEC3B restricts the replication of HIV-1 in HEK293 cells, while our laboratory clone of rhesus macaque APOBEC3B did not. We mapped the r...
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| Autors principals: | , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
2013
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3752335/ https://ncbi.nlm.nih.gov/pubmed/23542011 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virol.2013.03.003 |
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