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APOBEC3 Multimerization Correlates with HIV-1 Packaging and Restriction Activity in Living Cells
APOBEC3G belongs to a family of DNA cytosine deaminases that are involved in the restriction of a broad number of retroviruses including HIV-1. Prior studies have identified two distinct mechanistic steps in Vif-deficient HIV-1 restriction: packaging into virions and deaminating viral cDNA. APOBEC3A...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3977201/ https://ncbi.nlm.nih.gov/pubmed/24361275 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2013.12.014 |
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