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APOBEC3 Multimerization Correlates with HIV-1 Packaging and Restriction Activity in Living Cells

APOBEC3G belongs to a family of DNA cytosine deaminases that are involved in the restriction of a broad number of retroviruses including HIV-1. Prior studies have identified two distinct mechanistic steps in Vif-deficient HIV-1 restriction: packaging into virions and deaminating viral cDNA. APOBEC3A...

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Main Authors: Li, Jinhui, Chen, Yan, Li, Ming, Carpenter, Michael A., McDougle, Rebecca M., Luengas, Elizabeth M., Macdonald, Patrick J., Harris, Reuben S., Mueller, Joachim D.
格式: Artigo
語言:Inglês
出版: 2013
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3977201/
https://ncbi.nlm.nih.gov/pubmed/24361275
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2013.12.014
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