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Stereoselective biotransformation of ketamine in equine liver and lung microsomes

Stereoselectivity has to be considered for pharmacodynamic and pharmacokinetic features of ketamine. Stereoselective biotransformation of ketamine was investigated in equine microsomes in vitro. Concentration curves were constructed over time, and enzyme activity was determined for different substra...

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Библиографические подробности
Главные авторы: Schmitz, A., Portier, C. J., Thormann, W., Theurillat, R., Mevissen, M.
Формат: Artigo
Язык:Inglês
Опубликовано: 2008
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2821671/
https://ncbi.nlm.nih.gov/pubmed/19000264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2885.2008.00972.x
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