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Stereoselective biotransformation of ketamine in equine liver and lung microsomes

Stereoselectivity has to be considered for pharmacodynamic and pharmacokinetic features of ketamine. Stereoselective biotransformation of ketamine was investigated in equine microsomes in vitro. Concentration curves were constructed over time, and enzyme activity was determined for different substra...

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Bibliografiske detaljer
Main Authors: Schmitz, A., Portier, C. J., Thormann, W., Theurillat, R., Mevissen, M.
Format: Artigo
Sprog:Inglês
Udgivet: 2008
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2821671/
https://ncbi.nlm.nih.gov/pubmed/19000264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2885.2008.00972.x
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