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Stereoselective biotransformation of ketamine in equine liver and lung microsomes

Stereoselectivity has to be considered for pharmacodynamic and pharmacokinetic features of ketamine. Stereoselective biotransformation of ketamine was investigated in equine microsomes in vitro. Concentration curves were constructed over time, and enzyme activity was determined for different substra...

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Autors principals: Schmitz, A., Portier, C. J., Thormann, W., Theurillat, R., Mevissen, M.
Format: Artigo
Idioma:Inglês
Publicat: 2008
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2821671/
https://ncbi.nlm.nih.gov/pubmed/19000264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2885.2008.00972.x
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