Stereoselective glucuronidation of formoterol by human liver microsomes

AIMS: Formoterol is a β(2)-adrenoceptor agonist marketed as a racemic mixture of the active (R; R)- and inactive (S; S)-enantiomers (rac-formoterol). The drug produces prolonged bronchodilation by inhalation but there is significant interpatient variability in duration of effect. Previous work has s...

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Detaylı Bibliyografya
Asıl Yazarlar: Zhang, Mei, Fawcett, J Paul, Kennedy, Julia M, Shaw, John P
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Blackwell Science Inc 2000
Konular:
Original Articles
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2014895/
https://ncbi.nlm.nih.gov/pubmed/10671910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2125.2000.00133.x
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