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Biotransformation of caffeine in human liver microsomes from foetuses, neonates, infants and adults.

1. Caffeine metabolism was studied in human liver microsomes from foetuses (n = 10), neonates (n = 10), infants (n = 9) and adults (n = 5). Caffeine and its metabolites, 1-3-7-trimethyluric acid, paraxanthine, theophylline and theobromine, were assayed by h.p.l.c. Methoxyresorufin-O-demethylase acti...

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Autors principals: Cazeneuve, C, Pons, G, Rey, E, Treluyer, J M, Cresteil, T, Thiroux, G, D'Athis, P, Olive, G
Format: Artigo
Idioma:Inglês
Publicat: 1994
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1364894/
https://ncbi.nlm.nih.gov/pubmed/8054245
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