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Chirality Holds the Key for Potent Inhibition of the Botulinum Neurotoxin Serotype A Protease
[Image: see text] Botulinum neurotoxin serotype A (BoNT/A) is the most toxic protein known to man, and also a bioterrorism agent. As defined by our previous research targeting the etiological agent responsible for BoNT/A intoxication, a protease, we now report on the asymmetric synthesis of four new...
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| Main Authors: | , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2010
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2821465/ https://ncbi.nlm.nih.gov/pubmed/20092262 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ol902820z |
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