Identification of a Natural Product Antagonist against the Botulinum Neurotoxin Light Chain Protease

[Image: see text] Botulinum neurotoxins (BoNTs) are the etiological agents responsible for botulism, a disease characterized by peripheral neuromuscular blockade and a characteristic flaccid paralysis of humans. BoNTs are the most lethal known poisons affecting humans and have been recognized as a p...

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Autors principals: Eubanks, Lisa M., Šilhár, Peter, Salzameda, Nicholas T., Zakhari, Joseph S., Xiaochuan, Feng, Barbieri, Joseph T., Shoemaker, Charles B., Hixon, Mark S., Janda, Kim D.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2010
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2955888/
https://ncbi.nlm.nih.gov/pubmed/20959871
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml100074s
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