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Folding and assembly kinetics of procaspase-3
Caspases are vital to apoptosis and exist in the cell as inactive zymogens. Dimerization is central to procaspase activation because the active sites are comprised of loops from both monomers. Although initiator procaspases are stable monomers until activated on cell death scaffolds, the effector ca...
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| Main Authors: | , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Wiley Subscription Services, Inc., A Wiley Company
2009
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2821269/ https://ncbi.nlm.nih.gov/pubmed/19798740 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.259 |
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