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Folding and assembly kinetics of procaspase-3

Caspases are vital to apoptosis and exist in the cell as inactive zymogens. Dimerization is central to procaspase activation because the active sites are comprised of loops from both monomers. Although initiator procaspases are stable monomers until activated on cell death scaffolds, the effector ca...

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Detalhes bibliográficos
Main Authors: Milam, Sara L, Clark, A Clay
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2821269/
https://ncbi.nlm.nih.gov/pubmed/19798740
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.259
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