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Kinetic traps in the folding/unfolding of procaspase-1 CARD domain
We have examined the folding and unfolding of the caspase recruitment domain of procaspase-1 (CP1-CARD), a member of the α-helical Greek key protein family. The equilibrium folding/unfolding of CP1-CARD is described by a two-state mechanism, and the results show CP1-CARD is marginally stable with a...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2004
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2279836/ https://ncbi.nlm.nih.gov/pubmed/15273313 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.03521504 |
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