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Substitutions of prolines examine their role in kinetic trap formation of the caspase recruitment domain (CARD) of RICK
Caspase recruitment domains (CARDs) are small helical protein domains that adopt the Greek key fold. For the two CARDs studied to date, RICK-CARD and caspase-1-CARD (CP1-CARD), the proteins unfold by an apparent two-state process at equilibrium. However, the folding kinetics are complex for both pro...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2006
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2249761/ https://ncbi.nlm.nih.gov/pubmed/16501221 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1110/ps.051943006 |
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