Polypeptide Modulators of Caspase Recruitment Domain (CARD)-CARD-mediated Protein-Protein Interactions

The caspase recruitment domain (CARD) is present in a large number of proteins. Initially, the CARD was recognized as part of the caspase activation machinery. CARD-CARD interactions play a role in apoptosis and are responsible for the Apaf-1-mediated activation of procaspase-9 in the apoptosome. CA...

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Bibliographic Details
Main Authors: Palacios-Rodríguez, Yadira, García-Laínez, Guillermo, Sancho, Mónica, Gortat, Anna, Orzáez, Mar, Pérez-Payá, Enrique
Format: Artigo
Language:Inglês
Published: American Society for Biochemistry and Molecular Biology 2011
Subjects:
Signal Transduction
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3247988/
https://ncbi.nlm.nih.gov/pubmed/22065589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M111.255364
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