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Identification and validation of uterine stimulant methylergometrine as a potential inhibitor of caspase-1 activation

Inflammasomes are intracellular multiprotein complexes of the innate immune system. Upon an inflammatory insult, such as infection or intracellular damage, a nucleotide-binding oligomerization domain-like receptor (NLR) sensor protein and the adaptor protein ASC (apoptosis-associated speck-like prot...

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Detalhes bibliográficos
Publicado no:Apoptosis
Main Authors: García-Laínez, Guillermo, Sancho, Mónica, García-Bayarri, Vanessa, Orzáez, Mar
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5630661/
https://ncbi.nlm.nih.gov/pubmed/28755170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-017-1405-z
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