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BOK-MCL1 transmembrane interactions: a challenging target for cancer therapy

Myeloid cell leukemia 1 (MCL1) gene amplification occurs in a wide range of human cancers and protein overexpression associates with malignant cell growth and evasion of apoptosis. We recently reported that disrupting the interaction between the transmembrane domains of MCL1 and BCL-2 related ovaria...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Mol Cell Oncol
Egile Nagusiak: Sancho, Mónica, Orzáez, Mar
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis 2021
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC7849717/
https://ncbi.nlm.nih.gov/pubmed/33553610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/23723556.2020.1859918
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