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Intramolecular Interactions and Regulation of Cofactor Binding by the Four Repressive Elements in the Caspase Recruitment Domain-containing Protein 11 (CARD11) Inhibitory Domain

The CARD11 signaling scaffold transmits signaling between antigen receptors on B and T lymphocytes and the transcription factor NF-κB during the adaptive immune response. CARD11 activity is controlled by an inhibitory domain (ID), which participates in intramolecular interactions and prevents cofact...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Jattani, Rakhi P., Tritapoe, Julia M., Pomerantz, Joel L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4861409/
https://ncbi.nlm.nih.gov/pubmed/26884334
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M116.717322
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