Coordinated regulation of scaffold opening and enzymatic activity during CARD11 signaling

The activation of key signaling pathways downstream of antigen receptor engagement is critically required for normal lymphocyte activation during the adaptive immune response. CARD11 is a multidomain signaling scaffold protein required for antigen receptor signaling to NF-κB, c-Jun N-terminal kinase...

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Detalhes bibliográficos
Publicado no:J Biol Chem
Main Authors: Wang, Zhaoquan, Hutcherson, Shelby M., Yang, Chao, Jattani, Rakhi P., Tritapoe, Julia M., Yang, Yong-Kang, Pomerantz, Joel L.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2019
Assuntos:
Signal Transduction
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6779434/
https://ncbi.nlm.nih.gov/pubmed/31391255
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.009551
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