Mechanisms of Regulated and Dysregulated CARD11 Signaling in Adaptive Immunity and Disease

CARD11 functions as a key signaling scaffold that controls antigen-induced lymphocyte activation during the adaptive immune response. Somatic mutations in CARD11 are frequently found in Non-Hodgkin lymphoma, and at least three classes of germline CARD11 mutations have been described as the basis for...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Front Immunol
Main Authors: Bedsaul, Jacquelyn R., Carter, Nicole M., Deibel, Katelynn E., Hutcherson, Shelby M., Jones, Tyler A., Wang, Zhaoquan, Yang, Chao, Yang, Yong-Kang, Pomerantz, Joel L.
Format: Artigo
Jezik:Inglês
Izdano: Frontiers Media S.A. 2018
Teme:
Immunology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6156143/
https://ncbi.nlm.nih.gov/pubmed/30283447
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2018.02105
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