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A minimal regulatory domain in the C terminus of STIM1 binds to and activates ORAI1 CRAC channels
Store-operated Ca(2+) entry (SOCE) is a universal mechanism to increase intracellular Ca(2+) concentrations in non-excitable cells. It is initiated by the depletion of ER Ca(2+) stores, activation of stromal interaction molecule (STIM) 1 and gating of the Ca(2+) release activated Ca(2+) (CRAC) chann...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2821023/ https://ncbi.nlm.nih.gov/pubmed/19433061 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2009.05.020 |
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