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Protein Kinase C-induced Phosphorylation of Orai1 Regulates the Intracellular Ca(2+) Level via the Store-operated Ca(2+) Channel

Ca(2+) signals through store-operated Ca(2+) (SOC) channels, activated by the depletion of Ca(2+) from the endoplasmic reticulum, regulate various physiological events. Orai1 is the pore-forming subunit of the Ca(2+) release-activated Ca(2+) (CRAC) channel, the best characterized SOC channel. Orai1...

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Bibliografske podrobnosti
Main Authors: Kawasaki, Takumi, Ueyama, Takehiko, Lange, Ingo, Feske, Stefan, Saito, Naoaki
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2010
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2919135/
https://ncbi.nlm.nih.gov/pubmed/20534587
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.022996
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