Characterization of Streptococcus pyogenes β-NAD(+) Glycohydrolase: RE-EVALUATION OF ENZYMATIC PROPERTIES ASSOCIATED WITH PATHOGENESIS

The Gram-positive pathogen Streptococcus pyogenes injects a β-NAD(+) glycohydrolase (SPN) into the cytosol of an infected host cell using the cytolysin-mediated translocation pathway. In this compartment, SPN accelerates the death of the host cell by an unknown mechanism that may involve its β-NAD(+...

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Hauptverfasser: Ghosh, Joydeep, Anderson, Patricia J., Chandrasekaran, Sukantha, Caparon, Michael G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2010
Schlagworte:
Enzymology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820796/
https://ncbi.nlm.nih.gov/pubmed/20018886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.070300
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