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Characterization of Streptococcus pyogenes β-NAD(+) Glycohydrolase: RE-EVALUATION OF ENZYMATIC PROPERTIES ASSOCIATED WITH PATHOGENESIS

The Gram-positive pathogen Streptococcus pyogenes injects a β-NAD(+) glycohydrolase (SPN) into the cytosol of an infected host cell using the cytolysin-mediated translocation pathway. In this compartment, SPN accelerates the death of the host cell by an unknown mechanism that may involve its β-NAD(+...

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Detalhes bibliográficos
Main Authors: Ghosh, Joydeep, Anderson, Patricia J., Chandrasekaran, Sukantha, Caparon, Michael G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2820796/
https://ncbi.nlm.nih.gov/pubmed/20018886
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.070300
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