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Structural Basis of Streptococcus pyogenes Immunity to its NAD(+) Glycohydrolase Toxin

The virulence of Gram-positive bacteria is enhanced by toxins like the Streptococcus pyogenes β-NAD(+) glycohydrolase known as SPN. SPN-producing strains of S. pyogenes additionally express the protein immunity factor for SPN (IFS), which forms an inhibitory complex with SPN. We have determined crys...

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Bibliografische gegevens
Hoofdauteurs: Smith, Craig L., Ghosh, Joydeep, Elam, Jennifer Stine, Pinkner, Jerome S., Hultgren, Scott J., Caparon, Michael G., Ellenberger, Tom
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2011
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3056158/
https://ncbi.nlm.nih.gov/pubmed/21300288
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2010.12.013
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