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BACE1 and BACE2 Enzymatic Activities in Alzheimer’s Disease
β-Secretase is the rate limiting enzymatic activity in the production of the amyloid-β peptide (Aβ) and is thought to be involved in Alzheimer’s disease (AD) pathogenesis. Although BACE1 (β-site APP Cleaving Enzyme 1, EC 3.4.23.46) has received significant attention, the related BACE2 (EC 3.4.23.45)...
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| Hlavní autoři: | , , , , , |
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| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2009
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2819564/ https://ncbi.nlm.nih.gov/pubmed/19968762 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2009.06528.x |
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