BACE1 and BACE2 Enzymatic Activities in Alzheimer’s Disease

β-Secretase is the rate limiting enzymatic activity in the production of the amyloid-β peptide (Aβ) and is thought to be involved in Alzheimer’s disease (AD) pathogenesis. Although BACE1 (β-site APP Cleaving Enzyme 1, EC 3.4.23.46) has received significant attention, the related BACE2 (EC 3.4.23.45)...

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Detaylı Bibliyografya
Asıl Yazarlar: Ahmed, Rachel R., Holler, Christopher J., Webb, Robin L., Li, Feng, Beckett, Tina L., Murphy, M. Paul
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819564/
https://ncbi.nlm.nih.gov/pubmed/19968762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1471-4159.2009.06528.x
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