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Measurement and clinical monitoring of human lymphocyte clonality by massively parallel VDJ pyrosequencing

The complex repertoire of immune receptors generated by B and T cells enables recognition of diverse threats to the host organism. In this work, we show that massively parallel DNA sequencing of rearranged immune receptor loci can provide direct detection and tracking of immune diversity and expande...

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書誌詳細
主要な著者: Boyd, Scott D., Marshall, Eleanor L., Merker, Jason D., Maniar, Jay M., Zhang, Lyndon N., Sahaf, Bita, Jones, Carol D., Simen, Birgitte B., Hanczaruk, Bozena, Nguyen, Khoa D., Nadeau, Kari C., Egholm, Michael, Miklos, David B., Zehnder, James L., Fire, Andrew Z.
フォーマット: Artigo
言語:Inglês
出版事項: 2009
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819115/
https://ncbi.nlm.nih.gov/pubmed/20161664
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