Measurement and clinical monitoring of human lymphocyte clonality by massively parallel VDJ pyrosequencing

The complex repertoire of immune receptors generated by B and T cells enables recognition of diverse threats to the host organism. In this work, we show that massively parallel DNA sequencing of rearranged immune receptor loci can provide direct detection and tracking of immune diversity and expande...

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Библиографические подробности
Главные авторы: Boyd, Scott D., Marshall, Eleanor L., Merker, Jason D., Maniar, Jay M., Zhang, Lyndon N., Sahaf, Bita, Jones, Carol D., Simen, Birgitte B., Hanczaruk, Bozena, Nguyen, Khoa D., Nadeau, Kari C., Egholm, Michael, Miklos, David B., Zehnder, James L., Fire, Andrew Z.
Формат: Artigo
Язык:Inglês
Опубликовано: 2009
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819115/
https://ncbi.nlm.nih.gov/pubmed/20161664
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