High-throughput VDJ sequencing for quantification of minimal residual disease in chronic lymphocytic leukemia and immune reconstitution assessment

The primary cause of poor outcome following allogeneic hematopoietic cell transplantation (HCT) for chronic lymphocytic leukemia (CLL) is disease recurrence. Detection of increasing minimal residual disease (MRD) following HCT may permit early intervention to prevent clinical relapse; however, MRD q...

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Détails bibliographiques
Auteurs principaux: Logan, Aaron C., Gao, Hong, Wang, Chunlin, Sahaf, Bita, Jones, Carol D., Marshall, Eleanor L., Buño, Ismael, Armstrong, Randall, Fire, Andrew Z., Weinberg, Kenneth I., Mindrinos, Michael, Zehnder, James L., Boyd, Scott D., Xiao, Wenzhong, Davis, Ronald W., Miklos, David B.
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2011
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3248502/
https://ncbi.nlm.nih.gov/pubmed/22160699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1118357109
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