Individual Variation in the Germline Ig Gene Repertoire Inferred from Variable Region Gene Rearrangements

Individual variation in the Ig germline gene repertoire leads to individual differences in the combinatorial diversity of the Ab repertoire, but the study of such variation has been problematic. The application of high-throughput DNA sequencing to the study of rearranged Ig genes now makes this poss...

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Bibliografske podrobnosti
izdano v:J Immunol
Main Authors: Boyd, Scott D., Gaëta, Bruno A., Jackson, Katherine J., Fire, Andrew Z., Marshall, Eleanor L., Merker, Jason D., Maniar, Jay M., Zhang, Lyndon N., Sahaf, Bita, Jones, Carol D., Simen, Birgitte B., Hanczaruk, Bozena, Nguyen, Khoa D., Nadeau, Kari C., Egholm, Michael, Miklos, David B., Zehnder, James L., Collins, Andrew M.
Format: Artigo
Jezik:Inglês
Izdano: 2010
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4281569/
https://ncbi.nlm.nih.gov/pubmed/20495067
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1000445
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