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MT1-MMP is a crucial promotor of synovial invasion in human rheumatoid arthritis

OBJECTIVE: A hallmark of rheumatoid arthritis (RA) is invasion of the synovial pannus into cartilage and this step requires degradation of the collagen matrix. The aim of this study was to explore the role of one of the collagen-degrading matrix metalloproteinases (MMPs), membrane-type 1 MMP (MT1-MM...

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Bibliografiska uppgifter
Huvudupphovsmän: Miller, Mary-Clare, Manning, Hugh B., Jain, Abhilash, Troeberg, Linda, Dudhia, Jayesh, Essex, David, Sandison, Ann, Seiki, Motoharu, Nanchahal, Jagdeep, Nagase, Hideaki, Itoh, Yoshifumi
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2009
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Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819053/
https://ncbi.nlm.nih.gov/pubmed/19248098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.24331
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