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MT1-MMP is a crucial promotor of synovial invasion in human rheumatoid arthritis

OBJECTIVE: A hallmark of rheumatoid arthritis (RA) is invasion of the synovial pannus into cartilage and this step requires degradation of the collagen matrix. The aim of this study was to explore the role of one of the collagen-degrading matrix metalloproteinases (MMPs), membrane-type 1 MMP (MT1-MM...

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Detalhes bibliográficos
Main Authors: Miller, Mary-Clare, Manning, Hugh B., Jain, Abhilash, Troeberg, Linda, Dudhia, Jayesh, Essex, David, Sandison, Ann, Seiki, Motoharu, Nanchahal, Jagdeep, Nagase, Hideaki, Itoh, Yoshifumi
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2819053/
https://ncbi.nlm.nih.gov/pubmed/19248098
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/art.24331
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