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Cell Surface Collagenolysis Requires Homodimerization of the Membrane-bound Collagenase MT1-MMP

Pericellular degradation of interstitial collagens is a crucial event for cells to migrate through the dense connective tissue matrices, where collagens exist as insoluble fibers. A key proteinase that participates in this process is considered to be membrane-type 1 matrix metalloproteinase (MT1-MMP...

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Autori principali: Itoh, Yoshifumi, Ito, Noriko, Nagase, Hideaki, Evans, Richard D., Bird, Sarah A., Seiki, Motoharu
Natura: Artigo
Lingua:Inglês
Pubblicazione: The American Society for Cell Biology 2006
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC1679699/
https://ncbi.nlm.nih.gov/pubmed/17050733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E06-08-0740
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