MT-LOOP-dependent Localization of Membrane Type I Matrix Metalloproteinase (MT1-MMP) to the Cell Adhesion Complexes Promotes Cancer Cell Invasion

Localization of membrane type I matrix metalloproteinase (MT1-MMP) to the leading edge is thought to be a crucial step during cancer cell invasion. However, its mechanisms and functional impact on cellular invasion have not been clearly defined. In this report, we have identified the MT-LOOP, a loop...

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Autores principales: Woskowicz, Anna M., Weaver, Sarah A., Shitomi, Yasuyuki, Ito, Noriko, Itoh, Yoshifumi
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2013
Materias:
Cell Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3853264/
https://ncbi.nlm.nih.gov/pubmed/24165131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M113.496067
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