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Design and Synthesis of Selective Inhibitors of Placental Alkaline Phosphatase

Placental Alkaline Phosphatase (PLAP) is a tissue-restricted isozyme of the Alkaline Phosphatase (AP) superfamily. PLAP is an oncodevelopmental enzyme expressed during pregnancy and in a variety of human cancers, but its biological function remains unknown. We report here a series of catechol compou...

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Detalhes bibliográficos
Main Authors: Lanier, Marion, Sergienko, Eduard, Simão, Ana Maria, Su, Ying, Chung, Thomas, Millán, José Luis, Cashman, John R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818863/
https://ncbi.nlm.nih.gov/pubmed/20031422
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmc.2009.12.012
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