MUC16 provides immune protection by inhibiting synapse formation between NK and ovarian tumor cells

BACKGROUND: Cancer cells utilize a variety of mechanisms to evade immune detection and attack. Effective immune detection largely relies on the formation of an immune synapse which requires close contact between immune cells and their targets. Here, we show that MUC16, a heavily glycosylated 3-5 mil...

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מידע ביבליוגרפי
Main Authors: Gubbels, Jennifer AA, Felder, Mildred, Horibata, Sachi, Belisle, Jennifer A, Kapur, Arvinder, Holden, Helen, Petrie, Sarah, Migneault, Martine, Rancourt, Claudine, Connor, Joseph P, Patankar, Manish S
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2010
נושאים:
Research
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818693/
https://ncbi.nlm.nih.gov/pubmed/20089172
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-9-11
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