Peritoneal natural killer cells from epithelial ovarian cancer patients show an altered phenotype and bind to the tumour marker MUC16 (CA125)

The ovarian tumour marker MUC16 (CA125) inhibits the cytotoxic responses of human natural killer (NK) cells and down-regulates CD16. Here we show that approximately 10% of the peripheral blood NK cells (PBNK) from the epithelial ovarian cancer (EOC) patients are CD16(–) CD56(br) whereas 40% of the p...

Full description

Saved in:
Bibliographic Details
Main Authors: Belisle, Jennifer A, Gubbels, Jennifer A A, Raphael, Cara A, Migneault, Martine, Rancourt, Claudine, Connor, Joseph P, Patankar, Manish S
Format: Artigo
Language:Inglês
Published: Blackwell Science Inc 2007
Subjects:
Original Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2266014/
https://ncbi.nlm.nih.gov/pubmed/17617155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2007.02660.x
Tags: Add Tag
No Tags, Be the first to tag this record!

Similar Items