Peritoneal natural killer cells from epithelial ovarian cancer patients show an altered phenotype and bind to the tumour marker MUC16 (CA125)

The ovarian tumour marker MUC16 (CA125) inhibits the cytotoxic responses of human natural killer (NK) cells and down-regulates CD16. Here we show that approximately 10% of the peripheral blood NK cells (PBNK) from the epithelial ovarian cancer (EOC) patients are CD16(–) CD56(br) whereas 40% of the p...

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Main Authors: Belisle, Jennifer A, Gubbels, Jennifer A A, Raphael, Cara A, Migneault, Martine, Rancourt, Claudine, Connor, Joseph P, Patankar, Manish S
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 2007
Teme:
Original Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2266014/
https://ncbi.nlm.nih.gov/pubmed/17617155
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2567.2007.02660.x
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