Llwytho...

Dendrimer-based Tumor Cell Targeting of Fibroblast Growth Factor-1

Fibroblast Growth Factor Receptor (FGFR) is overexpressed in a wide variety of tumors, and therefore is an attractive target for drug delivery. Recombinant FGF-1 was purified and attached to a fifth-generation (G5) polyamidoamine dendrimer. The specific binding and internalization of this conjugate...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Thomas, Thommey P., Shukla, Rameshwer, Kotlyar, Alina, Kukowska-Latallo, Jola, Baker, James R.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818523/
https://ncbi.nlm.nih.gov/pubmed/19962894
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2009.11.065
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