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Targeting the efficacy of a dendrimer-based nanotherapeutic in heterogeneous xenograft tumors in vivo

Our earlier studies have shown the in vitro and in vivo targeting of a generation 5 (G5) dendrimer-based multifunctional conjugate that contained folic acid (FA) as the targeting agent and methotrexate (MTX) as the chemotherapeutic drug. To clinically apply the synthesized G5-FA-MTX nanotherapeutic,...

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Detalhes bibliográficos
Main Authors: Myc, Andrzej, Kukowska-Latallo, Jolanta, Cao, Peter, Swanson, Ben, Battista, Julianna, Dunham, Thomas, Baker, James R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818998/
https://ncbi.nlm.nih.gov/pubmed/20010426
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/CAD.0b013e328334560f
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