Targeted gadolinium-loaded dendrimer nanoparticles for tumor-specific magnetic resonance contrast enhancement

A target-specific MRI contrast agent for tumor cells expressing high affinity folate receptor was synthesized using generation five (G5) of polyamidoamine (PAMAM) dendrimer. Surface modified dendrimer was functionalized for targeting with folic acid (FA) and the remaining terminal primary amines of...

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Main Authors: Swanson, Scott D, Kukowska-Latallo, Jolanta F, Patri, Anil K, Chen, Chunyan, Ge, Song, Cao, Zhengyi, Kotlyar, Alina, East, Andrea T, Baker, James R
格式: Artigo
語言:Inglês
出版: Dove Medical Press 2008
主題:
Original Research
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527674/
https://ncbi.nlm.nih.gov/pubmed/18686779
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