Targeted gadolinium-loaded dendrimer nanoparticles for tumor-specific magnetic resonance contrast enhancement

A target-specific MRI contrast agent for tumor cells expressing high affinity folate receptor was synthesized using generation five (G5) of polyamidoamine (PAMAM) dendrimer. Surface modified dendrimer was functionalized for targeting with folic acid (FA) and the remaining terminal primary amines of...

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Detalhes bibliográficos
Main Authors: Swanson, Scott D, Kukowska-Latallo, Jolanta F, Patri, Anil K, Chen, Chunyan, Ge, Song, Cao, Zhengyi, Kotlyar, Alina, East, Andrea T, Baker, James R
Formato: Artigo
Idioma:Inglês
Publicado em: Dove Medical Press 2008
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2527674/
https://ncbi.nlm.nih.gov/pubmed/18686779
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