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Osmolyte-induced conformational changes in the Hsp90 molecular chaperone

Osmolytes are small molecules that play a central role in cellular homeostasis and the stress response by maintaining protein thermodynamic stability at controlled levels. The underlying physical chemistry that describes how different osmolytes impact folding free energy is well understood, however...

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Détails bibliographiques
Auteurs principaux: Street, Timothy O, Krukenberg, Kristin A, Rosgen, Jörg, Bolen, D Wayne, Agard, David A
Format: Artigo
Langue:Inglês
Publié: Wiley Subscription Services, Inc., A Wiley Company 2010
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2817839/
https://ncbi.nlm.nih.gov/pubmed/19890989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.282
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