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Osmolyte-induced conformational changes in the Hsp90 molecular chaperone

Osmolytes are small molecules that play a central role in cellular homeostasis and the stress response by maintaining protein thermodynamic stability at controlled levels. The underlying physical chemistry that describes how different osmolytes impact folding free energy is well understood, however...

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Bibliografische gegevens
Hoofdauteurs: Street, Timothy O, Krukenberg, Kristin A, Rosgen, Jörg, Bolen, D Wayne, Agard, David A
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Wiley Subscription Services, Inc., A Wiley Company 2010
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2817839/
https://ncbi.nlm.nih.gov/pubmed/19890989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.282
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