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Osmolyte-induced conformational changes in the Hsp90 molecular chaperone

Osmolytes are small molecules that play a central role in cellular homeostasis and the stress response by maintaining protein thermodynamic stability at controlled levels. The underlying physical chemistry that describes how different osmolytes impact folding free energy is well understood, however...

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Detalhes bibliográficos
Main Authors: Street, Timothy O, Krukenberg, Kristin A, Rosgen, Jörg, Bolen, D Wayne, Agard, David A
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2817839/
https://ncbi.nlm.nih.gov/pubmed/19890989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/pro.282
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