Laddar...
Client-Loading Conformation of the Hsp90 Molecular Chaperone Revealed in the Cryo-EM Structure of the Human Hsp90:Hop Complex
Hsp90 is an essential molecular chaperone required for the folding and activation of many hundreds of cellular “client” proteins. The ATP-dependent chaperone cycle involves significant conformational rearrangements of the Hsp90 dimer and interaction with a network of cochaperone proteins. Little is...
Sparad:
| Huvudupphovsmän: | , |
|---|---|
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
2011
|
| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3144320/ https://ncbi.nlm.nih.gov/pubmed/21700222 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2011.04.023 |
| Taggar: |
Lägg till en tagg
Inga taggar, Lägg till första taggen!
|