Purification of ras GTPase activating protein from bovine brain.

In cytosolic extracts of bovine brain, we detected ras GTPase activating protein (GAP) activity that stimulated the GTP hydrolytic activity of normal c-Ha-ras p21 but not that of the oncogenic [Val12]p21 variant. GAP was purified 19,500-fold by a five-column procedure involving DEAE-Sephacel, Sephar...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Gibbs, J B, Schaber, M D, Allard, W J, Sigal, I S, Scolnick, E M
Format: Artigo
Langue:Inglês
Publié: 1988
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC281680/
https://ncbi.nlm.nih.gov/pubmed/3293047
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